cell health profiling bioapplication module Search Results


arra yscan vti hcs reader cellomics cell health profiling bioapplication  (Thermo Fisher)
86
Thermo Fisher arra yscan vti hcs reader cellomics cell health profiling bioapplication
Summary of HSC for drug discovery from TCM
Arra Yscan Vti Hcs Reader Cellomics Cell Health Profiling Bioapplication, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
arra yscan vti hcs reader cellomics cell health profiling bioapplication - by Bioz Stars, 2026-04
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cell health profile bioapplication  (Thermo Fisher)
90
Thermo Fisher cell health profile bioapplication
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Health Profile Bioapplication, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell health profile bioapplication/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
cell health profile bioapplication - by Bioz Stars, 2026-04
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cell health profiling bioapplication module [ ]  (Thermo Fisher)
90
Thermo Fisher cell health profiling bioapplication module [ ]
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Health Profiling Bioapplication Module [ ], supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell health profiling bioapplication module [ ]/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
cell health profiling bioapplication module [ ] - by Bioz Stars, 2026-04
90/100 stars
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cell health profiling bioapplication software  (Thermo Fisher)
86
Thermo Fisher cell health profiling bioapplication software
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Health Profiling Bioapplication Software, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell health profiling bioapplication software/product/Thermo Fisher
Average 86 stars, based on 1 article reviews
cell health profiling bioapplication software - by Bioz Stars, 2026-04
86/100 stars
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cell health profiling  (BioApplications Inc)
90
BioApplications Inc cell health profiling
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Health Profiling, supplied by BioApplications Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell health profiling/product/BioApplications Inc
Average 90 stars, based on 1 article reviews
cell health profiling - by Bioz Stars, 2026-04
90/100 stars
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cell health profiling bioapplication  (Thermo Fisher)
90
Thermo Fisher cell health profiling bioapplication
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Health Profiling Bioapplication, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell health profiling bioapplication/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
cell health profiling bioapplication - by Bioz Stars, 2026-04
90/100 stars
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cell viability cell health profiling bioapplication software  (Thermal Scientific)
90
Thermal Scientific cell viability cell health profiling bioapplication software
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Viability Cell Health Profiling Bioapplication Software, supplied by Thermal Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell viability cell health profiling bioapplication software/product/Thermal Scientific
Average 90 stars, based on 1 article reviews
cell viability cell health profiling bioapplication software - by Bioz Stars, 2026-04
90/100 stars
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cell health profiling bioapplication v3 software  (Thermo Fisher)
90
Thermo Fisher cell health profiling bioapplication v3 software
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Cell Health Profiling Bioapplication V3 Software, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell health profiling bioapplication v3 software/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
cell health profiling bioapplication v3 software - by Bioz Stars, 2026-04
90/100 stars
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hcs studio bioapplication cell health profiling v4  (Thermo Fisher)
90
Thermo Fisher hcs studio bioapplication cell health profiling v4
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Hcs Studio Bioapplication Cell Health Profiling V4, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hcs studio bioapplication cell health profiling v4/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
hcs studio bioapplication cell health profiling v4 - by Bioz Stars, 2026-04
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of raft polymerization  (BioApplications Inc)
90
BioApplications Inc of raft polymerization
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Of Raft Polymerization, supplied by BioApplications Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/of raft polymerization/product/BioApplications Inc
Average 90 stars, based on 1 article reviews
of raft polymerization - by Bioz Stars, 2026-04
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of small molecule aza-bodipy  (BioApplications Inc)
90
BioApplications Inc of small molecule aza-bodipy
I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection <t>Bioapplication</t> was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.
Of Small Molecule Aza Bodipy, supplied by BioApplications Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/of small molecule aza-bodipy/product/BioApplications Inc
Average 90 stars, based on 1 article reviews
of small molecule aza-bodipy - by Bioz Stars, 2026-04
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Image Search Results


Summary of HSC for drug discovery from TCM

Journal: Chinese Medicine

Article Title: High content screening for drug discovery from traditional Chinese medicine

doi: 10.1186/s13020-019-0228-y

Figure Lengend Snippet: Summary of HSC for drug discovery from TCM

Article Snippet: LX-2 hepatic stellate cell proliferation , Hepatic stellate cell proliferation is a marker of liver fibrosis , Cellomics Arra yScan VTI HCS Reader Cellomics Cell Health Profiling BioApplication , Identify the active components of Danshen for anti-liver fibrosis , Salvianolic acid B, caffeic acid and rosmarinic acid , [ ] .

Techniques: Immunostaining, Translocation Assay, Confocal Microscopy, Software, Microscopy, Staining, Over Expression, Activity Assay, Imaging, Marker, Inhibition, Permeability, Stable Transfection, Expressing

I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection Bioapplication was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.

Journal: PLoS ONE

Article Title: High Content Analysis Provides Mechanistic Insights on the Pathways of Toxicity Induced by Amine-Modified Polystyrene Nanoparticles

doi: 10.1371/journal.pone.0108025

Figure Lengend Snippet: I321N1 and HepG2 cells were exposed to vehicle (ctrl) or increasing concentrations of PS-COOH or PS-NH 2 NPs for 24 hours and analysed by HCA. The Spot Detection Bioapplication was used to analyse the Lysotracker green positive vesicles inside the exposed cells. A. Representative images of cells exposed to vehicle or 25 µg/ml PS-NH 2 NPs showing the increased Lysotracker green fluorescence and the analysis performed using the Spot Detector Bioapplication. Scale bar = 20 µm. B. Dose-dependent changes parameters associated with Lysotracker green positive vesicles: counts, area and intensity of Lysotracker green positive vescicles for each cell were calculated; dose dependent changes in individual spots were also recorded. C. Comparison among spot counts, spot total area and spot total intensity/cell within each cell line. The results suggest that increasing concentrations of PS-NH 2 NPs cause swelling of lysosomes, as indicated by increased Lysotracker green intensity, followed by a reduction in spot counts and reduciton in the spot area/cell and their intensity, indicative of lysosomal rupture. Data are shown as average +/− SD of object numbers, fluorescence intensity, area per cell, or average fluorescence intensity per identified object respectively from a representative experiment. Data were fitted with a gaussian curve for visual purposes only.

Article Snippet: Dr. Chandrasekaran at Thermo Scientific USA implemented a custom made algorithm so that the Cell Health Profile bioapplication reported field view details (average intensity per cell using a fixed threshold in each field acquired) for the following parameters: cell numbers, nuclear size, nuclear intensity, TMRM intensity, Fluo-4 intensity, Lysotracker green intensity and TOPRO-3 intensity.

Techniques: Fluorescence, Comparison